Related Experiment Video
Updated: Aug 18, 2026

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
Published on: January 7, 2019
Effectiveness of psychotherapy for both endogenous and nonendogenous depression in older adult outpatients
Abstract:
This study explored the effectiveness of brief psychotherapies for treatment of elderly depressed outpatients. All were in a current episode of major depressive disorder, but half the sample (n = 15) presented with endogenous symptomatology as well. Patients were assigned to either behavioral, cognitive, or insight-oriented psychotherapy for 16 sessions over a 12-week period. Evaluation occurred before and after therapy, and at four times during a 1-year follow-up interval. Nonendogenous patients responded more favorably to psychotherapy; this differential effect persisted throughout follow-up. Significant improvement, however, was made by some endogenous patients. One-third were not depressed by termination of therapy, and seven others were notably improved. Eight of 15 had not relapsed at 1-year follow-up.
Related Concept Videos
Antidepressant Drugs: MAOIs and Other Agents
Psychotherapy
Elements Crucial for Effective Psychotherapy
The Therapeutic Alliance
The therapeutic alliance refers to the relationship between the therapist and the client. The alliance strengthens when the therapist and the client engage in a nurturing, supportive, trusting, empathetic, and respectful relationship, improving therapeutic outcomes. Therapists must monitor this relationship...
Psychodynamic Therapy
Electroconvulsive Therapy
Interpersonal Psychotherapy

