Plasma cholesterol and lipoprotein lowering effect of Anna Pavala Sindhooram

Plasma lipid and lipoprotein lowering effect of Anna Pavala Sindhooram (APS), a Sidha medicinal preparation was investigated in normal rabbits, chicken and men, and in hypercholesterolemic rabbits. The drug exhibited a marked hypolipaemic and hypocholesterolemic action in the three species studied. In rabbits, marked reduction was observed in very low density lipoprotein cholesterol, while in chicks and in humans low density lipoprotein cholesterol was also reduced significantly when compared to the levels measured before the administration of the drug. The drug enhances faecal elimination of lipids and bile acids in atherosclerotic rabbits.