Management and follow-up of cervical intraepithelial neoplasia treated by CO2 laser vaporization method

Forty-four patients with cervical intraepithelial neoplasia (CIN) II and 31 patients with CIN III were followed up for up to 6 months after cervical cone vaporization with carbon dioxide laser. In addition to colposcopy and pap smear, all patients underwent cervical biopsies as part of their follow-up. This protocol permitted a diagnosis of persistent disease in the presence of normal colposcopy and pap smear.