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Analgesic dilemma in chronic hemodialysis patients

Frieder Keller1, Anke Schwarz

  • 1Freie Universität, Klinikum Steglitz, Medizinische Klinik Nephrologie, Dialysezentrum des KfH, Hindenburgdamm 30, 1000 Berlin 45 F.R.G.

Pain
|September 1, 1983
PubMed

Insights

Analgesic drug abuse caused end-stage renal disease in 31% of patients studied. This addiction persisted even during chronic hemodialysis, highlighting a significant challenge in patient management.

Area of Science:

  • Nephrology
  • Addiction Medicine
  • Psychiatry

Background:

  • Analgesic drug abuse is a significant cause of end-stage renal disease (ESRD).
  • Substance addiction poses challenges in managing patients with chronic kidney disease, including those on hemodialysis.
  • Understanding the psychological profile of patients with drug-induced ESRD is crucial for effective treatment.

Purpose of the Study:

  • To investigate the prevalence of analgesic drug abuse as a cause of ESRD.
  • To assess the persistence of drug addiction in patients undergoing chronic hemodialysis.
  • To identify potential personality correlates associated with drug addiction leading to ESRD.

Main Methods:

  • Cross-sectional investigation involving 122 patients.
  • Data collection on drug abuse history and renal disease etiology.
  • Assessment of addiction status in patients on chronic hemodialysis.
  • Exploration of personality traits in a subset of patients.

Main Results:

  • Analgesic drug abuse was identified as the cause of ESRD in 31% of the 122 patients.
  • Addiction to analgesics and tranquilizers persisted in a significant number of patients even after initiating chronic hemodialysis.
  • A specific personality type, characterized by depression and chronic headache, was observed in patients with drug addiction leading to ESRD.

Conclusions:

  • Analgesic drug abuse is a substantial contributor to end-stage renal disease.
  • Chronic hemodialysis does not resolve underlying drug addiction in affected patients.
  • Psychological factors, such as a depressive personality profile, may be linked to analgesic addiction and subsequent ESRD.

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