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Updated: Aug 18, 2026

Heterotypic Three-dimensional In Vitro Modeling of Stromal-Epithelial Interactions During Ovarian Cancer Initiation and Progression
Published on: August 28, 2012
[Clinico-morphological characteristics of marginal epithelial ovarian tumors]
Abstract:
Clinico-morphological features of 228 proliferating epithelial ovarian tumors of various histological patterns were studied. The group under study consisted of 135 serous (59.2%), 54 mucinous (23.7%) and 39 endometroid cystadenomas (17.1%). These tumors spread by implantation only. Metastases were registered in 20.2% of cases. Their incidence increased significantly in younger patients of reproductive age and in those with bilateral lesions, ascitis, cystic-solid and papillary types of tumor growth, mucinous tumors and invasive neoplasms. A correlation was established between the degree of tumor proliferation and the clinical course of the disease: 79.4% of patients of the atypical proliferation group revealed apparent manifestations of malignancy.
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