[Effect of various vagal functional conditions on the blood flow of abdominal organs]

In 21 mongrel dogs blood flow was measured in different gastrointestinal organs under fasting conditions, vagal stimulation with 2-desoxy-D-glucose and vagotomy. The examinations were performed in anaesthesia with the microsphere method. Basal blood flow was found in corpus, fundus and antrum below 0,5 ml/g X min, whereas in the region of the small curvature values of 0,7 ml/g X min were observed. Vagotomy decreases flowrates especially in the mucosa of the stomach except in the region of the antrum. There a significant increase was measured. The stimulated bloodflow shows a similar effect by a vagotomy, but on an elevated lovel. Observations over the time of 3 weeks revealed that bloodflow changes due to vagotomy are not long lasting over that time. Only a decrease can be observed in the region of the antrum. Also in the other abdominal organs bloodflow changes due to vagotomy are terminated to a short time interval. Except the bloodflow changes in the gallbladder lasts longer than 4 weeks. From this investigation the conclusion can be drawn that vagotomy does not cause long lasting and radical bloodflow changes in the abdomen.