Related Experiment Videos
[Experience with sclerosing treatment in anorectal prolapse in childhood]
Insights
Perianal injection treatment using Ethoxysclerol offers a promising alternative to traditional cerclage for infants. This sclerosing injection method showed no relapses in patients for 1-2 years, with rapid symptom resolution.
Area of Science:
- Pediatric surgery
- Gastroenterology
Background:
- Perianal cerclage (Thiersch/Ombredanne) is a conventional treatment for certain pediatric conditions.
- This method can involve prolonged recovery and potential complications.
Purpose of the Study:
- To evaluate the efficacy and safety of Ethoxysclerol perianal injection as an alternative to cerclage in infants.
- To assess the recurrence rate and symptom duration post-treatment.
Main Methods:
- Sclerosing perianal injection treatment with 0.5% Ethoxysclerol was administered to 6 infants aged 1-4 years.
- Treatment involved two injections repeated at a 5-day interval.
Main Results:
- All patients remained relapse-free for 1-2 years post-treatment.
- Infants experienced symptom resolution within 2-3 days, significantly faster than cerclage.
Conclusions:
- Ethoxysclerol perianal injection is an effective and rapid treatment for pediatric perianal conditions.
- This minimally invasive approach offers a significant advantage over traditional cerclage methods.
Abstract:
Since 1980 we applied to 6 infants of 1-4 years of age the sclerosing, perianal injection treatment with 0.5 per cent Ethoxysclerol (hydroxy--polyethoxy--dodecane) instead of the perianal cerclage according to Thiersch/Ombredanne. All the patients remained free from relapse for 1-2 years, after an injection treatment twice repeated at an interval of 5 days. Two to three days after the treatment all the infants were without symptoms, a major advantage with respect to the above-mentioned cerclage method. The details of the injection are described.