[Complications in the treatment of chronic glomerulonephritis]

In a retrospective study involving 97 patients with histologically confirmed glomerulonephritis the complications which led to the breaking off or changing of an immunosuppressive therapy [Prednison monotherapy (n = 39), Prednison cyclophospohamide therapy (n = 13), Prednison azathioprin therapy (n = 49), Indometazin therapy (n = 25)] were examined. Of 97 patients treated repeatedly over long periods, 22 suffered complications which caused the therapy to be broken off or changed. Because of the risk involved, immunosuppressive therapy of glomerulonephritis should only be practised by institutions specializing in nephrology.