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Updated: Aug 14, 2026

Rat Model of Widespread Cerebral Cortical Demyelination Induced by an Intracerebral Injection of Pro-Inflammatory Cytokines
Published on: September 21, 2021
[Clinical picture and epidemiology of disseminated sclerosis]
Abstract:
The prevalence and characteristic features of the clinical course of disseminated sclerosis in the population of the Far North were studied. The proportion of disseminated sclerosis among organic diseases of the central nervous system in this area is considerably lower (0.36%) than in many regions and areas of Western and Eastern Siberia and especially in the central regions of the European part of the USSR. A considerable difference in the incidence of this disease between the local population and newcomers is noted, namely 7% and 93%, respectively. Local population displays a more progressive course of the disease. No cases of disseminated sclerosis have been recorded among the indigenous population i.e., yakutes and small nationalities of the North.
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