Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Is the lecithin/sphingomyelin ratio outdated?

D K James, V R Tindall, T Richardson

    British Journal of Obstetrics and Gynaecology
    |November 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    IPSS-M downstaging before transplantation does not improve the prognosis of patients with myelodysplastic neoplasms.

    Bone marrow transplantation·2026
    Same author

    Author Correction: Consistent FFP2-masking as part of reducing viral respiratory infections on medical wards for allogeneic hematopoietic stem cell transplantation.

    Scientific reports·2025
    Same author

    Detecting Changes in Comfort, Pain, and Mobility Over Clinical Milestones for Individuals With Lower Limb Loss.

    Canadian prosthetics & orthotics journal·2024
    Same author

    Allogeneic Hematopoietic Stem Cell Transplantation in Refractory Multiple Myeloma-A Retrospective Multicenter Analysis.

    European journal of haematology·2024
    Same author

    Consistent FFP2-masking as part of reducing viral respiratory infections on medical wards for allogeneic hematopoietic stem cell transplantation.

    Scientific reports·2024
    Same author

    Aerial strategies advance volcanic gas measurements at inaccessible, strongly degassing volcanoes.

    Science advances·2020
    Same journal

    Livial: an economic appraisal.

    British journal of obstetrics and gynaecology·2000
    Same journal

    Livial: a review of clinical studies.

    British journal of obstetrics and gynaecology·2000
    Same journal

    Place of birth and shoulder dystocia.

    British journal of obstetrics and gynaecology·1999
    Same journal

    The value of the negative predictive values.

    British journal of obstetrics and gynaecology·1999
    Same journal

    Splenectomy during pregnancy: an option in treatment of autoimmune thrombocytopenic purpura.

    British journal of obstetrics and gynaecology·1999
    Same journal

    Third trimester abortion: is compassion enough?

    British journal of obstetrics and gynaecology·1999
    See all related articles

    The lecithin/sphingomyelin (L/S) ratio test for fetal lung maturity is declining in use, causing laboratory inefficiencies. A regional reorganization of fetal lung maturity testing is proposed to address this issue.

    Area of Science:

    • Obstetrics and Gynecology
    • Clinical Chemistry
    • Neonatology

    Background:

    • The lecithin/sphingomyelin (L/S) ratio in amniotic fluid has been a key indicator of fetal lung maturity.
    • However, its clinical utility has diminished in recent years.
    • This decline impacts laboratory service efficiency and patient care.

    Purpose of the Study:

    • To analyze the trend in L/S ratio testing requests in Manchester from 1975-1981.
    • To identify reasons for the observed decrease in L/S ratio test utilization.
    • To propose a regional strategy for fetal lung maturity assessment.

    Main Methods:

    • Retrospective review of L/S ratio test requests at a Manchester laboratory.
    • Analysis of request trends over a seven-year period (1975-1981).

    Related Experiment Videos

  • Discussion of potential factors influencing test usage, including St Mary's Hospital data.

    • Main Results:

    • A significant and consistent decline in L/S ratio test requests was observed in the final 18 months of the study period.
    • This reduction led to laboratory service inconvenience and inefficiency.
    • The study highlights a shift away from traditional L/S ratio testing.

    Conclusions:

    • The declining use of the L/S ratio test necessitates a re-evaluation of fetal lung maturity assessment protocols.
    • A regional reorganization of laboratory services for fetal lung maturity testing is recommended.
    • Implementing updated strategies will improve efficiency and diagnostic accuracy.