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Summary
Stored blood containing Toxoplasma organisms can infect recipients. This study demonstrates that blood stored for up to 28 days at 4°C remains infectious, causing toxoplasmosis in rabbits upon transfusion.
Area of Science:
- Medical Microbiology
- Parasitology
- Infectious Diseases
Background:
- Toxoplasma gondii is an opportunistic parasite.
- Understanding transmission routes is crucial for prevention.
Purpose of the Study:
- To determine if blood stored with anticoagulants remains infectious for Toxoplasma.
Main Methods:
- Human blood (heparin or citrate) inoculated with Toxoplasma.
- Stored at 4°C for up to 28 days.
- Injected into rabbit ear veins; transfused infected rabbit blood.
Main Results:
- Rabbits injected with stored blood developed toxoplasmosis.
- Transfusion of blood from infected rabbits also caused disease.
Conclusions:
- Blood stored with anticoagulants can transmit Toxoplasma.
- Infectivity is maintained for at least 28 days under refrigeration.