Leiomyoma presenting as prolonged fever, anemia, and thrombocytosis

Area of Science:

• Gastroenterology
• Pediatric Oncology
• Pathology

Background:

• Leiomyomas are benign smooth muscle tumors that can occur in various locations, including the gastrointestinal tract.
• Large bowel leiomyomas are rare, especially in pediatric patients.
• Understanding the clinical presentation is crucial for early diagnosis and management.

Observation:

• A 2-year-old boy presented with prolonged fever, anemia, and thrombocytosis.
• These clinical manifestations are unusual for common pediatric conditions.
• The patient's symptoms were consistent with a leiomyoma of the large bowel.

Findings:

• The case highlights a rare presentation of large bowel leiomyoma in a pediatric patient.
• The clinical triad of fever, anemia, and thrombocytosis in this context parallels findings in a previously reported adult case.
• This suggests a potential common pathophysiological pathway or diagnostic pattern.

Implications:

• Increased awareness of these manifestations can aid in the early diagnosis of large bowel leiomyoma in children.
• Prompt diagnosis may allow for pre-surgical investigation into the pathogenesis of these associated hematological abnormalities.
• This case contributes to the limited literature on pediatric gastrointestinal leiomyomas, informing clinical practice and research.