Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Amphibian brain gangliosides: pattern analysis by two-dimensional thin-layer chromatography.

L N Irwin, K Schwartz

    Comparative Biochemistry and Physiology. B, Comparative Biochemistry
    |January 1, 1983
    PubMed
    Summary

    Amphibian brain gangliosides showed distinct differences between families but quantitative variations within the same family or genus. This research explores amphibian neurochemistry and evolutionary relationships.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Correlates of HIV-1 control after combination immunotherapy.

    Nature·2025
    Same author

    Combination immunotherapy induces post-intervention control of HIV.

    Research square·2025
    Same author

    Effects of atipamezole on selected physiologic parameters in cynomolgus macaques (Macaca fascicularis).

    Journal of medical primatology·2023
    Same author

    Caregiving burden among informal caregivers of African American cancer survivors.

    Journal of cancer survivorship : research and practice·2020
    Same author

    Porcine Reproductive and Respiratory Syndrome virus reduces feed efficiency, digestibility, and lean tissue accretion in grow-finish pigs.

    Translational animal science·2020
    Same author

    Identification and Characterization of a Phase-Variable Element That Regulates the Autotransporter UpaE in Uropathogenic Escherichia coli.

    mBio·2018

    Area of Science:

    • Neuroscience
    • Biochemistry
    • Evolutionary Biology

    Background:

    • Gangliosides are crucial glycosphingolipids in vertebrate nervous systems.
    • Amphibian neurobiology and evolutionary divergence remain incompletely understood.
    • Comparative analysis of brain lipids can illuminate evolutionary pathways.

    Purpose of the Study:

    • To investigate the diversity of gangliosides in amphibian brains.
    • To determine if ganglioside profiles correlate with amphibian taxonomy.
    • To explore the evolutionary implications of ganglioside composition in amphibians.

    Main Methods:

    • Gangliosides were extracted from the brains of ten amphibian species.
    • Species represented six genera across two orders.

    Related Experiment Videos

  • Two-dimensional thin-layer chromatography (2D-TLC) was employed for analysis.

    • Main Results:

    • Distinct qualitative differences in ganglioside profiles were observed at the family level.
    • Variations within the same family or genus were predominantly quantitative.
    • The findings suggest a correlation between ganglioside composition and higher taxonomic ranks.

    Conclusions:

    • Amphibian ganglioside profiles exhibit significant evolutionary divergence at the family level.
    • Quantitative variations may reflect adaptations within genera or families.
    • Ganglioside analysis provides a valuable tool for understanding amphibian evolutionary relationships.