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Segmental ejection fraction in normal subjects.

L R Llerena, A Toruncha, L Llerena

    Cor Et Vasa
    |January 1, 1983
    PubMed
    Summary
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    This study assessed left ventricular regional wall motion using a modified area method in 30 healthy individuals. The findings provide reference values for segmental ejection fraction, aiding in the evaluation of cardiac performance.

    Area of Science:

    • Cardiology
    • Medical Imaging
    • Physiology

    Background:

    • Assessing left ventricular (LV) function is crucial in cardiology.
    • Standard methods for evaluating regional wall motion can be complex.
    • A need exists for reliable reference data in normal subjects.

    Purpose of the Study:

    • To evaluate left ventricular regional wall motion in normal subjects.
    • To establish reference values for segmental ejection fraction using a modified area method.
    • To provide a basis for comparison in clinical assessments of cardiac performance.

    Main Methods:

    • A modified area method, based on Gelberg et al., was employed.
    • Left ventricular cineangiograms were acquired in the right anterior oblique projection at 48 frames/s.

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  • End-diastolic and end-systolic frames were divided into 8 regions using a grid; segmental ejection fraction was calculated based on area changes.
  • Main Results:

    • Mean segmental ejection fraction values were calculated for 8 distinct regions of the left ventricle.
    • Values ranged from 42 +/- 15% (posterobasal) to 59 +/- 6% (anterolateral-proximal).
    • Significant variability was noted, particularly in the anterobasal and posterobasal segments.

    Conclusions:

    • The modified area method provides a feasible approach to assess LV regional wall motion.
    • The derived segmental ejection fraction values serve as valuable reference data for normal individuals.
    • These reference values are useful for comparing and evaluating left ventricular performance in patient populations.