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Related Experiment Video

Updated: Jun 9, 2026

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
06:10

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Published on: June 12, 2021

Intra-aortic balloon assistance without a pump.

D A Sideris, J N Nanas, D N Chrysos

    European Heart Journal
    |August 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

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    A novel intra-aortic compression chamber system (CCS) improved cardiac output and related hemodynamic parameters in dogs and patients. This device shows potential for treating cardiogenic shock, especially when other options are unavailable.

    Area of Science:

    • Cardiovascular Physiology
    • Medical Devices
    • Critical Care Medicine

    Background:

    • Cardiogenic shock remains a critical condition with limited treatment options.
    • Existing mechanical circulatory support devices can be complex or unavailable.
    • There is a need for simple, potentially portable devices to improve hemodynamic function in shock.

    Purpose of the Study:

    • To evaluate the efficacy of a novel intra-aortic compression chamber system (CCS).
    • To assess the hemodynamic effects of CCS in an animal model and in patients with cardiogenic shock.
    • To determine the potential clinical utility of CCS as a treatment for cardiogenic shock.

    Main Methods:

    • The study utilized an intra-aortic compression chamber system (CCS) in 19 anesthetized dogs and 7 patients.

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    Last Updated: Jun 9, 2026

    Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
    06:10

    Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

    Published on: June 12, 2021

    The Intra-Aortic Balloon Pump
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    The Intra-Aortic Balloon Pump

    Published on: February 5, 2021

    Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock
    07:39

    Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock

    Published on: August 16, 2021

  • The CCS involved an intra-aortic balloon inflated intermittently to augment aortic pressure.
  • Hemodynamic parameters including cardiac output, aortic compliance, and cardiac power were measured before, during, and after CCS inflation.

    • Main Results:

    • CCS inflation significantly increased cardiac output (7.8%), aortic compliance (12.8%), cardiac power (36.7%), and coronary sinus outflow (23.6%) in dogs.
    • In patients with cardiogenic shock, CCS increased cardiac output by 4.1% over prolonged periods.
    • Left ventricular end-diastolic pressure did not change significantly during CCS use.

    Conclusions:

    • The intra-aortic compression chamber system (CCS) demonstrates a capacity to improve key hemodynamic indicators.
    • CCS may serve as a valuable tool in managing clinical cardiogenic shock.
    • Its potential utility is particularly noted in scenarios lacking intra-aortic balloon pump availability or when a portable solution is preferred.