Simultaneous spectrophotometric determination of amodiaquine-primaquine mixtures in dosage forms

Using 0.1N hydrochloric acid as solvent, mixtures of amodiaquine and primaquine have been measured at 282 and 342 nm. The concentration of each can then be calculated by solving 2 simultaneous equations. Excellent recoveries from authentic samples were obtained and the method proved suitable for routine analysis.