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Behavior and anxiety: physiologic mechanisms.

M Lader

    The Journal of Clinical Psychiatry
    |November 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    This study differentiates normal from clinical anxiety, reviewing psycho- and neurophysiologic research. Current models inadequately explain human anxiety, necessitating further clinical investigation into its symptoms and natural history.

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    Area of Science:

    • Psychology
    • Neuroscience
    • Clinical Medicine

    Background:

    • Distinguishing between normal and clinical anxiety is crucial for understanding and treatment.
    • Existing theories on the etiology and nature of anxiety require further examination.

    Purpose of the Study:

    • To describe the distinction between normal and clinical anxiety.
    • To review research on the psycho- and neurophysiology of anxiety.
    • To present neurophysiologic models and assess their explanatory power for human anxiety.

    Main Methods:

    • Literature review of psycho- and neurophysiologic research on anxiety.
    • Presentation and discussion of two major neurophysiologic models derived from animal studies.

    Main Results:

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    • Current neurophysiologic models do not fully explain the complexities of human anxiety.
    • The review highlights gaps in understanding the psycho- and neurophysiological underpinnings of anxiety.

    Conclusions:

    • Existing models are insufficient to explain human anxiety.
    • Further clinical studies focusing on anxiety symptoms and natural history are recommended.
    • Enhanced understanding of anxiety requires integrated clinical and basic research approaches.