Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Case of immunoblastic sarcoma (IBS)].

K Ebe, S Eguchi, K Yamakawa

    Gan No Rinsho. Japan Journal of Cancer Clinics
    |October 1, 1983
    PubMed
    Summary

    This case report details a patient initially diagnosed with immunoblastic lymphadenopathy that progressed to immunoblastic sarcoma. The study highlights the challenges in managing this rare hematologic malignancy and its potential for aggressive transformation.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Prognostic significance of histologic parameters of soft tissue sarcomas.

    Cancer·1992
    Same author

    A reassessment of histologic classification and an immunohistochemical study of 88 retinoblastomas. A special reference to the advent of bipolar-like cells.

    Cancer·1992
    Same author

    [Elemental analysis of hilar and mediastinal lymph nodes in idiopathic pulmonary fibrosis].

    Nihon Kyobu Shikkan Gakkai zasshi·1992
    Same author

    Relationship between inhibitor of extrathyroidal 5'-deiodinase activity and serum free fatty acid in children with nonthyroidal illness and acute ketosis.

    Endocrinologia japonica·1992
    Same author

    [Changes in seizure-triggering threshold and after discharge duration in seizure susceptibility].

    No to shinkei = Brain and nerve·1992
    Same author

    Mechanism of extracellular ATP-stimulated phosphoinositide hydrolysis in rat glioma C6 cells.

    The Journal of pharmacology and experimental therapeutics·1992

    Area of Science:

    • Hematology
    • Oncology
    • Pathology

    Background:

    • Immunoblastic lymphadenopathy (IBL) is a rare condition.
    • Malignant transformation of IBL into immunoblastic sarcoma (IBS) is a documented but infrequent event.

    Observation:

    • A 48-year-old female presented with cough and fever, with a history of IBL diagnosed two years prior.
    • Generalized lymphadenopathy and a left hilar mass were noted; initial treatment with irradiation led to temporary improvement.
    • The patient experienced relapses, developing multiple pulmonary lesions, pancytopenia, and bone metastases.

    Findings:

    • Autopsy revealed lymph nodes with histological evidence of immunoblastic sarcoma.
    • A pulmonary lesion demonstrated features of immunoblastic lymphadenopathy, indicating a complex disease presentation.

    Related Experiment Videos

    Implications:

    • This case underscores the aggressive nature and potential for transformation of IBL into IBS.
    • It highlights the diagnostic and therapeutic challenges in managing such rare hematologic malignancies.
    • Further research into the pathogenesis and optimal treatment strategies for IBL and its transformation is warranted.