Quantitative analysis of EEG power spectra in experimental hepatic encephalopathy

During galactosamine-induced acute liver failure in white male Wistar rats, EEG was recorded at regular intervals. Spectral analysis was done as described by Kropveld and co-workers in 1983. The specificity of the anomalies in the power-density spectra is tested by comparing the changing patterns with those caused by several pharmaceutical agents--ether, diazepam, pentobarbital. Quantification of the observed anomalies is discussed.