Mesothelioma of the AV node
Related Experiment Video
Updated: Aug 13, 2026

Orthotopic Implantation and Peripheral Immune Cell Monitoring in the II-45 Syngeneic Rat Mesothelioma Model
Published on: October 2, 2015
Abstract:
A 21-month-old boy died suddenly six months after presenting with heart murmur and second-degree atrioventricular (AV) block. Autopsy revealed a mesothelioma completely replacing the AV node and extending into the central fibrous body. The bundle of His and bundle branches were not involved. Mesothelioma of the AV node is a rare cause of supra-His (AV) block, arrhythmias, and sudden death.
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