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Pancreatic somatostatinoma. Clinical features and physiological implications
Lancet (London, England)
|March 26, 1977
Summary
This study reports the first pancreatic tumor producing somatostatin. This tumor caused hormonal imbalances and digestive issues, suggesting a link between somatostatin hypersecretion and these clinical abnormalities.
Area of Science:
- Endocrinology
- Gastroenterology
- Oncology
Background:
- Somatostatin is a hormone with diverse physiological roles.
- Pancreatic islet D cells normally produce somatostatin.
- Tumors producing somatostatin have not been previously documented.