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Updated: Aug 18, 2026

Study of Phagolysosome Biogenesis in Live Macrophages
Published on: March 10, 2014
The lymphocyte lysosomes in ontogeny of man
Abstract:
During intrauterine fetal development, the gradual formation of enzyme-positive lysosomes containing acid phosphatase, beta-glucuronidase, and N-acetyl-beta-glucosaminidase takes place within peripheral lymphocytes. During the first 5 decades of human life the lysosomal apparatus of lymphocytes containing the above enzymes exhibits relative stability whereas the final stages of man's ontogenetic development between 6th and 9th decade of life are characterized by the disintegration of enzyme-positive lysosomes.
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