[Polymorphic ocular involvement in relapsing polychondritis: an early, not always recognized symptom].

Area of Science:

• Rheumatology
• Ophthalmology
• Genetics

Background:

• Relapsing polychondritis (RP) is a rare systemic inflammatory disease of unknown cause.
• It primarily affects cartilaginous structures, including the ears, nose, and joints.
• Cardiovascular and ocular systems can also be involved in potentially destructive inflammatory lesions.

Observation:

• This report details three cases where patients presented with multiple ocular complications and arthropathy.
• These symptoms were noted as early indicators of relapsing polychondritis.
• The presentation highlights the potential for RP to manifest initially with non-cartilaginous symptoms.

Findings:

• Arthropathy and ocular complications can be early and significant presenting features of relapsing polychondritis.
• The findings suggest a need for heightened awareness of RP in patients with these initial symptoms.
• Early diagnosis is crucial for managing this rare and potentially destructive condition.

Implications:

• Recognizing arthropathy and ocular issues as early signs may lead to faster diagnosis of relapsing polychondritis.
• This could improve patient outcomes by enabling timely intervention and management.
• Further research into the etiology and early diagnostic markers of relapsing polychondritis is warranted.