Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Fetal scalp catecholamines during labor.

P Bistoletti, L Nylund, H Lagercrantz

    American Journal of Obstetrics and Gynecology
    |December 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Genetic testing for familial hypercholesterolemia among survivors of acute coronary syndrome.

    Journal of internal medicine·2018
    Same author

    A lateral-to-mesial organization of human ventral visual cortex at birth.

    Brain structure & function·2018
    Same author

    Severity of atopic disease inversely correlates with intestinal microbiota diversity and butyrate-producing bacteria.

    Allergy·2014
    Same author

    Cranial ultrasound and MRI at term age in extremely preterm infants.

    Archives of disease in childhood. Fetal and neonatal edition·2009
    Same author

    Road traffic accident risk in patients with diabetes mellitus receiving blood glucose-lowering drugs. Prospective follow-up study.

    Diabetic medicine : a journal of the British Diabetic Association·2009
    Same author

    Therapeutic hypothermia can be induced and maintained using either commercial water bottles or a "phase changing material" mattress in a newborn piglet model.

    Archives of disease in childhood·2009
    Same journal

    Double versus single emergency cervical cerclage combined with vaginal progesterone: a multicenter, non-blinded, randomized controlled trial.

    American journal of obstetrics and gynecology·2026
    Same journal

    Fibroblast heterogeneity and abnormal phenotype transition in vaginal wall prolapse at single-nucleus transcriptional resolution.

    American journal of obstetrics and gynecology·2026
    Same journal

    Early patient removal of urinary catheters after urogynecologic surgery, a randomized trial.

    American journal of obstetrics and gynecology·2026
    Same journal

    Standard vs. Lower Pressure Pneumoperitoneum in Laparoscopic Gynecologic Surgery: A Randomized Controlled Trial.

    American journal of obstetrics and gynecology·2026
    Same journal

    Association of Surgical Approach with Oncologic Outcomes in Low-Risk Cervical Cancer.

    American journal of obstetrics and gynecology·2026
    Same journal

    Trends in Infertility Treatments by Race, Ethnicity, Socioeconomic Status, and Region in U.S. Birth Certificates from Live Births: 2011-2022.

    American journal of obstetrics and gynecology·2026
    See all related articles

    Fetal stress during labor, indicated by low scalp blood pH and abnormal heart rates, significantly elevates plasma norepinephrine and epinephrine. These catecholamine levels, important indicators of fetal well-being, were higher than in resting adults.

    Area of Science:

    • Obstetrics and Gynecology
    • Fetal Physiology
    • Neonatal Medicine

    Background:

    • Fetal stress during labor can impact neonatal outcomes.
    • Catecholamines, such as norepinephrine and epinephrine, are key stress indicators.
    • Understanding fetal catecholamine responses is crucial for monitoring labor.

    Purpose of the Study:

    • To investigate the relationship between fetal stress markers and plasma catecholamine levels.
    • To analyze the correlation between fetal scalp blood pH, heart rate patterns, and catecholamine concentrations.
    • To determine the influence of maternal analgesia on fetal catecholamine levels.

    Main Methods:

    • Collected fetal scalp blood samples from 129 fetuses during the first stage of labor.
    • Analyzed plasma norepinephrine and epinephrine concentrations using high-performance liquid chromatography.

    Related Experiment Videos

  • Correlated catecholamine levels with fetal scalp blood pH and fetal heart rate patterns.

    • Main Results:

    • Median norepinephrine levels (9.2 nmol/L) and epinephrine levels (0.5 nmol/L) were observed in fetuses with pH > 7.25.
    • Significantly higher catecholamine concentrations were found when fetal scalp blood pH was below 7.26 (p < 0.001).
    • Elevated norepinephrine levels were associated with abnormal fetal heart rate patterns; maternal analgesia had no effect in uncomplicated labor.

    Conclusions:

    • Fetal stress, indicated by low pH and abnormal heart rates, leads to increased catecholamine release.
    • Plasma catecholamine levels serve as sensitive indicators of fetal distress during labor.
    • Monitoring fetal catecholamines may aid in assessing fetal well-being and guiding obstetric interventions.