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[Thermoregulation in prolonged antiorthostatic hypokinesia]
Zhurnal Nevropatologii I Psikhiatrii Imeni S.S. Korsakova (Moscow, Russia : 1952)
|January 1, 1978
Summary
Antiorthostatic hypokinesia disrupts thermoregulation, causing temperature discomfort and progressive disturbances in heat regulation dynamics. Skin temperature changes and altered reflex responses indicate impaired body heat control during prolonged bed rest.
Area of Science:
- Human physiology
- Environmental medicine
- Space medicine
Context:
- Investigates physiological responses to simulated microgravity.
- Focuses on thermoregulation during prolonged antiorthostatic hypokinesia.
- Utilizes a -4 degree head-down tilt model.
Purpose:
- To assess thermoregulation function during 49 days of antiorthostatic hypokinesia.
- To identify changes in skin temperature and thermoregulatory reflexes.
- To characterize the dynamics of thermoregulation under reduced body loading.
Summary:
- Daily axillary thermometry, skin thermotopography, and Shcherbak reflex tests were performed on 32 male volunteers over 49 days of -4 degree antiorthostatic hypokinesia.
- Initial temperature discomfort was linked to blood redistribution; later, progressive disturbances in thermoregulational dynamics emerged.
- These included altered oral-caudal and proximal-distal skin temperature correlations and impaired thermoregulatory reflex responses.
Impact:
- Reveals significant thermoregulatory challenges associated with prolonged hypokinesia.
- Highlights the progression of heat regulation disturbances over time.
- Provides insights into physiological adaptations and deconditioning relevant to spaceflight and bed rest studies.