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Transdermal scopolamine delivery system (TRANSDERM-V) and acute angle-closure glaucoma
Annals of Ophthalmology
|November 1, 1983
Summary
Transdermal scopolamine delivery systems can trigger acute angle-closure glaucoma. This adverse event occurred in a 58-year-old woman four days after using the patch.
Area of Science:
- Ophthalmology
- Pharmacology
Background:
- Transdermal scopolamine delivery systems are used for motion sickness and postoperative nausea.
- Ophthalmic side effects are rare but possible with systemic drug absorption.
Observation:
- A 58-year-old woman presented with unilateral acute angle-closure glaucoma.
- The onset of symptoms occurred four days after the application of a transdermal scopolamine patch (TRANSDERM-V).
Findings:
- The patient's presentation suggests a potential causal link between transdermal scopolamine and acute angle-closure glaucoma.
- This case highlights a rare but serious ocular adverse event associated with the medication.
Implications:
- Clinicians should consider transdermal scopolamine as a potential trigger for angle-closure glaucoma in susceptible individuals.
- Ophthalmologists should be aware of this association when evaluating patients with acute glaucoma, especially those using transdermal patches.