Changes in the electrophoretic pattern of salivary peroxidase at the middle of the menstrual cycle
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Updated: Jul 21, 2026

Performing Vaginal Lavage, Crystal Violet Staining, and Vaginal Cytological Evaluation for Mouse Estrous Cycle Staging Identification
Published on: September 15, 2012
Abstract:
Salivary peroxidase activity is known to increase at the middle of the menstrual cycle, and we report changes in electrophoretic patterns of salivary peroxidase over the same period. Peroxidase during the early follicular and late luteal phases of the menstrual cycle has been resolved into three forms by polyacrylamide gel electrophoresis. An additional, low mobility peroxidase has been detected at midcycle when two electrophoretic forms occurring at other times are reduced; this is coincident with the peak in total peroxidase activity. Available evidence suggests that this ovulatory peroxidase represents a catalytically active aggregate of the peroxidases normally present in saliva.
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