Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Practical limitations of epidemiologic methods.

A M Lilienfeld

    Environmental Health Perspectives
    |October 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Epidemiologic studies, including demographic and observational research, face challenges like data accuracy and bias. Despite limitations, these methods are crucial for understanding disease causes in human populations.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    EPIDEMIOLOGY OF CARDIOVASCULAR DISEASE. INTRODUCTION.

    A listing of research in the cardiovascular field·2014
    Same author

    Leukemia in children exposed to multiple risk factors.

    The New England journal of medicine·2010
    Same author

    Sigmodal in obstetrics; clinical observations with a report of three reactions.

    Bulletin of the School of Medicine (Baltimore, Md.)·2010
    Same author

    Declining trends in mortality from cerebrovascular disease at ages 10-65 years: a test of validity.

    Neuroepidemiology·1989
    Same author

    Risk factors for ischemic stroke: a prospective study in Rochester, Minnesota.

    Annals of neurology·1987
    Same author

    Inter- and intra-pathologist variability in the diagnosis of gestational trophoblastic neoplasia.

    Obstetrics and gynecology·1987
    Same journal

    A New Start.

    Environmental health perspectives·2026
    Same journal

    Time-Varying Exposure to Element Mixtures and Children's Cognition at 5 Years of Age: Findings from the New Hampshire Birth Cohort Study.

    Environmental health perspectives·2026
    Same journal

    Effect of Household Air Pollution on the Gut Microbiome and Virome of Adult Women Living in Uganda.

    Environmental health perspectives·2026
    Same journal

    Comparison of Temperature-Mortality Associations across the Middle East Using Different Exposure Estimation Approaches.

    Environmental health perspectives·2026
    Same journal

    Workflow for Statistical Analysis of Environmental Mixtures.

    Environmental health perspectives·2026
    Same journal

    Effects of Extreme Heat Exposure on Heatstroke and Liver Injury in Mice: The Role of PPARα.

    Environmental health perspectives·2026
    See all related articles

    Area of Science:

    • Epidemiology
    • Environmental Health
    • Biostatistics

    Background:

    • Epidemiologic methods are vital for understanding disease etiology.
    • Demographic, retrospective, and prospective observational studies are key research designs.
    • These studies face inherent limitations impacting data interpretation.

    Purpose of the Study:

    • To categorize and discuss the limitations of various epidemiologic study designs.
    • To illustrate challenges using examples of mortality and environmental exposure studies.
    • To highlight the continued necessity of human-based research in epidemiology.

    Main Methods:

    • Review of demographic studies, including a mortality study on nuclear fallout and leukemia.
    • Analysis of retrospective study limitations, such as recall bias and survivor bias.

    Related Experiment Videos

  • Examination of prospective study challenges, exemplified by a microwave radiation study.

    • Main Results:

    • Demographic studies face issues with death certificate accuracy, population estimates, and ecological fallacy.
    • Retrospective studies are prone to recall bias, selection bias, and survivor bias.
    • Prospective studies, while valuable, can suffer from small sample sizes and difficulties in data collection.

    Conclusions:

    • Epidemiologic studies, despite their limitations, have been instrumental in identifying etiological factors.
    • Addressing methodological challenges is essential for robust epidemiologic research.
    • Human-based observational studies remain indispensable for advancing public health knowledge.