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Related Experiment Videos

Hepatitis A in Swedish foreign travellers.

S Iwarson, M Wahl

    Developments in Biological Standardization
    |January 1, 1983
    PubMed
    Summary

    Scandinavians have low hepatitis A virus (HAV) antibody levels, increasing travel risks. However, HAV incidence in Swedish travelers to the Mediterranean has decreased, likely due to improved regional hygiene standards.

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    Area of Science:

    • Hepatology
    • Infectious Diseases
    • Epidemiology

    Background:

    • Scandinavians exhibit low seroprevalence of antibodies to hepatitis A virus (anti-HAV), below 25% in individuals under 50.
    • This low immunity renders the Scandinavian population particularly susceptible to hepatitis A infection when traveling to hyperendemic regions.

    Purpose of the Study:

    • To assess the incidence of hepatitis A among Swedish travelers to Mediterranean countries.
    • To evaluate changes in hepatitis A prevalence over time in this demographic.

    Main Methods:

    • Utilized Sweden's notifiable disease registry to track hepatitis A cases in travelers.
    • Compared hepatitis A incidence rates in Mediterranean travelers during the early 1970s versus 1980.

    Main Results:

    • Hepatitis A prevalence in Mediterranean travelers decreased from approximately 1 in 3000 in the early 1970s to 1 in 6000 in 1980.
    • This decline was observed even in travelers not receiving gammaglobulin prophylaxis.
    • Prevalence was significantly higher in travelers to North Africa, the Middle East, Tropical Africa, and Asia.

    Conclusions:

    • The decreasing incidence of hepatitis A in Swedish travelers to the northern Mediterranean is likely attributable to improved socioeconomic and hygienic conditions in those areas.
    • Despite declining rates in the northern Mediterranean, significant risks remain for travelers to other regions like North Africa, the Middle East, and Asia.

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