Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Vein interposition as a pathway for peripheral nerve regeneration].

G Rigoni, J Smahel, D T Chiu

    Handchirurgie, Mikrochirurgie, Plastische Chirurgie : Organ Der Deutschsprachigen Arbeitsgemeinschaft Fur Handchirurgie : Organ Der Deutschsprachigen Arbeitsgemeinschaft Fur Mikrochirurgie Der Peripheren Nerven Und Gefasse : Organ Der V
    |December 1, 1983
    PubMed
    Summary

    Autologous vein grafts showed comparable results to nerve grafts for small peripheral nerve defects. However, nerve grafts were superior for bridging larger nerve gaps in rabbit models.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Highly photostable wide-dynamic-range pH sensitive semiconducting polymer dots enabled by dendronizing the near-IR emitters.

    Chemical science·2017
    Same author

    Who and how in the regulation of mitochondrial cristae shape and function.

    Biochemical and biophysical research communications·2017
    Same author

    What childhood obesity prevention programmes work? A systematic review and meta-analysis.

    Obesity reviews : an official journal of the International Association for the Study of Obesity·2015
    Same author

    Microfluidics for single-cell genetic analysis.

    Lab on a chip·2014
    Same author

    Periodontal maintenance following scaling and root planing. A randomized single-center study comparing minocycline treatment and daily oral irrigation with water.

    Minerva stomatologica·2014
    Same author

    Salivary levels of IgA in healthy subjects undergoing active orthodontic treatment.

    Minerva stomatologica·2014

    Area of Science:

    • Regenerative Medicine
    • Neurosurgery
    • Biomaterials Science

    Background:

    • Peripheral nerve injuries often require surgical repair to restore function.
    • Autologous nerve grafting is a gold standard but limited by donor site morbidity.
    • Vein grafts are an alternative biomaterial for nerve defect bridging.

    Purpose of the Study:

    • To compare the efficacy of autologous vein grafts versus autologous nerve grafts in bridging peripheral nerve defects.
    • To evaluate the functional recovery in rabbit models using these two grafting techniques.

    Main Methods:

    • Sciatic nerve defects of 10-20 mm were created bilaterally in rabbits.
    • One side was bridged with an autologous nerve graft, the contralateral side with an autologous vein graft.

    Related Experiment Videos

  • Functional outcomes were assessed comparatively between the two graft types.

    • Main Results:

    • Comparable functional recovery was observed for both nerve and vein grafts in bridging small (10 mm) nerve defects.
    • Autologous nerve grafts demonstrated superior outcomes compared to vein grafts when bridging larger defects (20 mm).

    Conclusions:

    • Autologous vein grafts are a viable option for small peripheral nerve gaps.
    • Autologous nerve grafts remain the preferred method for larger peripheral nerve defects due to superior functional restoration.