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[Multiple tumors in the upper aerodigestive tract--a retrospective study]
Laryngologie, Rhinologie, Otologie
|November 1, 1983
Summary
The incidence of multiple primary neoplasms in the upper aerodigestive tract is rising. Patients with initial cancers should be monitored for new, secondary tumors, particularly after oral cavity or larynx cancers.
Area of Science:
- Oncology
- Otorhinolaryngology
- Cancer Research
Context:
- Increasing incidence of multiple primary neoplasms observed in the upper aerodigestive tract.
- Study analyzed 1231 patients with neoplasms, with 110 (8.9%) developing a second tumor.
- Oral cavity tumors showed twice the incidence of second tumors compared to other locations.
Purpose:
- To investigate the incidence and patterns of multiple primary neoplasms in the upper aerodigestive tract.
- To identify specific primary tumor sites associated with a higher risk of secondary neoplasms.
- To determine the time interval between first and secondary tumor development.
Summary:
- A significant percentage of upper aerodigestive tract neoplasm patients develop secondary tumors, with oral cavity and larynx cancers posing higher risks.
- The lung is a common site for secondary tumors after laryngeal cancer, while the hypopharynx and larynx are common after oral cavity cancers.
- The average time between the first and second neoplasm diagnosis was 4.4 years.
Impact:
- Highlights the need for vigilant follow-up in cancer patients to detect secondary neoplasms.
- Recommends including screening for second primary tumors in the follow-up therapy protocols.
- Informs clinical practice regarding risk stratification and surveillance strategies for upper aerodigestive tract cancer survivors.