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Related Experiment Videos

The 'morning glory syndrome' - a mesodermal defect?

A G Dempster, W R Lee, J V Forrester

    Ophthalmologica. Journal International D'Ophtalmologie. International Journal of Ophthalmology. Zeitschrift Fur Augenheilkunde
    |January 1, 1983
    PubMed
    Summary

    Morning Glory Syndrome is a rare optic disc malformation. This case details its clinical, imaging, and pathological features, including associated retinal and optic nerve abnormalities.

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    Area of Science:

    • Ophthalmology
    • Neuro-ophthalmology
    • Medical Imaging

    Background:

    • Morning Glory Syndrome is a rare congenital optic disc anomaly.
    • Understanding its varied presentations is crucial for diagnosis and management.

    Observation:

    • A case of unilateral Morning Glory Syndrome is presented.
    • Detailed clinical, ultrasonographic, CT scan, and pathological findings are described.

    Findings:

    • The malformation involved a peripapillary scleral defect, absent lamina cribrosa, and optic nerve retrodisplacement.
    • Associated findings included exudative retinal detachment, retinal atrophy, gliosis, and peripapillary pigment epithelium proliferation.
    • Further features comprised retinal schisis, absence of meninges replaced by fibroadipose tissue and smooth muscle, optic nerve atrophy, and a vascular plexus.

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    Implications:

    • This case highlights the complex anatomical variations associated with Morning Glory Syndrome.
    • Comprehensive evaluation is essential for patients with this rare condition.
    • Pathological correlation aids in understanding the pathogenesis of optic disc malformations.