Dissolution of struvite calculi by hemiacidrin solution.

Area of Science:

• Urology
• Nephrology
• Infectious Diseases

Background:

• Struvite calculi formation is associated with urinary tract infections caused by urease-producing bacteria.
• Complete removal of struvite calculi is crucial for preventing recurrent infections and stone formation.

Observation:

• Two patient cases with renal struvite calculi are presented.
• 10% hemiacidrin (Renacidin) irrigation was used for stone dissolution after surgical removal.
• Nephrostomy tubes were placed, and irrigation was initiated upon confirmation of residual calculi.

Findings:

• Hemiacidrin irrigation, when performed with strict aseptic technique and precautions, safely dissolves struvite calculi.
• Monitoring included urine cultures, electrolytes, and nephrotomograms to assess efficacy and adverse effects.

Implications:

• Hemiacidrin irrigation presents a viable adjunctive therapy for managing residual struvite calculi.
• This approach may help reduce the risk of recurrent urinary tract infections and stone formation.
• Further research could explore optimal irrigation protocols and long-term outcomes.