[Change in the renin-angiotensin-aldosterone system in the process of aging]

The results of the studies performed indicate changes in homeostasis of the renin-angiotensin-aldosterone system in old people. A basal level of the blood renin activity and aldosterone concentration decreases, whereas the humoral mechanism sensitivity to regulatory actions of the sympathico-adrenal and hypothalamic-hypophyseal systems increases. The changes mentioned are associated with alterations of intrarenal hemodynamics and electrolyte balance in the organism.