[Prostatic phosphomonoesterases in rats of different ages both intact and after gonadectomy]

The study of age changes in the activity of the rat prostatic acid and alkaline phosphatases within normal and under conditions of androgenic insufficiency has shown that the phosphomonoesterase content (nmol Rn/organ per min) increases with advancing age, whereas castration of the adult and infantile rats is accompanied by their significant decrease. The concentration of acid and alkaline phosphatase grows after early postnatal gonadectomy (nmol Rn/g of the tissue per min) without marked alterations in the enzyme content. The results obtained indicate that the hormonal control of acid and alkaline phosphatases is dependent on the androgen level of the organism.