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High-effective aluminium free phosphate binder. In vitro and in vivo studies
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association
|January 1, 1983
Abstract:
For the purpose of intestinal phosphate binding we have developed aluminium free natural polymers consisting of heteropolyuronic acid charged with different cations. The in vitro experiments showed an efficacy two to three times greater than Aludrox. During up to six months of clinical application no serious side effects have been detected, constipation ceased and serum phosphate was maintained in an acceptable range.