Signs and symptoms as predictors of outcome: a report from the International Pilot Study of Schizophrenia

Related Experiment Video

Updated: Aug 18, 2026

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
05:52

Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis

Published on: November 21, 2013

W T Carpenter, J J Bartko, J S Strauss

    The American Journal of Psychiatry
    |August 1, 1978
    PubMed

    More Related Videos

    Development of a Virtual Reality Assessment of Everyday Living Skills10:32

    Development of a Virtual Reality Assessment of Everyday Living Skills

    Published on: April 24, 2014

    Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study07:30

    Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

    Published on: August 18, 2020

    Related Concept Videos

    Schizophrenia01:17

    Schizophrenia

    Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those diagnosed.
    Positive Symptoms Schizophrenia: Hallucinations and Delusions01:26

    Positive Symptoms Schizophrenia: Hallucinations and Delusions

    Schizophrenia is a complex psychiatric disorder characterized by a range of symptoms that significantly impact cognition, behavior, and emotional regulation. Among these, the positive symptoms stand out as they involve the addition or exaggeration of normal mental functions, deviating markedly from typical behavior and perception. Hallucinations and delusions are prominent positive symptoms, each profoundly affecting the individual's experience of reality.
    Hallucinations
    Hallucinations in...
    Negative and Cognitive Symptoms of Schizophrenia01:30

    Negative and Cognitive Symptoms of Schizophrenia

    Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
    Negative Symptoms
    Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
    Biological Causes of Schizophrenia01:29

    Biological Causes of Schizophrenia

    Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
    Genetic Factors in Schizophrenia
    The genetic basis of schizophrenia is strongly supported by family and twin studies.
    Psychological and Sociocultural Causes of Schizophrenia01:29

    Psychological and Sociocultural Causes of Schizophrenia

    Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
    Positive Symptoms of Schizophrenia: Hallucinations and Delusions01:30

    Positive Symptoms of Schizophrenia: Hallucinations and Delusions

    Schizophrenia is a complex mental health disorder that can manifest with various positive symptoms, including thought, movement, and behavior disorders. These symptoms significantly disrupt cognitive and motor functions, leading to profound effects on an individual's ability to engage with the world.
    Thought Disorders
    Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes loosely...