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Related Experiment Videos

Trace element changes in hair during pregnancy: preliminary study.

H S Dang, D D Jaiswal, U Mehta

    The Science of the Total Environment
    |November 1, 1983
    PubMed
    Summary

    Pregnancy affects trace element levels in hair. While scalp hair showed no significant changes in copper (Cu), zinc (Zn), and manganese (Mn), pubic hair revealed lower Zn levels in late pregnancy.

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    Area of Science:

    • Biochemistry
    • Trace Element Analysis
    • Human Physiology

    Background:

    • Trace elements like copper (Cu), zinc (Zn), and manganese (Mn) are essential for various physiological processes.
    • Hair analysis offers a non-invasive method to assess long-term exposure and metabolic changes of trace elements.
    • Understanding trace element dynamics during pregnancy is crucial for maternal and fetal health.

    Purpose of the Study:

    • To investigate the changes in Cu, Zn, and Mn concentrations in human scalp and pubic hair during pregnancy.
    • To determine if pregnancy status significantly alters the levels of these essential trace elements in different hair types.

    Main Methods:

    • Neutron activation analysis (NAA) was employed to quantify Cu, Zn, and Mn concentrations.
    • Scalp and pubic hair samples were collected from both non-pregnant and pregnant female subjects.

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  • Analysis reliability was confirmed using certified reference materials (Bovine Liver, Orchard Leaves).

    • Main Results:

    • No significant differences in Cu, Zn, and Mn levels were observed in scalp hair between pregnant and non-pregnant subjects.
    • Pubic hair from subjects in the ninth month of pregnancy exhibited significantly lower Zn levels.
    • A steady decline in Cu and Zn levels was noted in pubic hair during the last trimester of pregnancy, with Mn levels remaining stable.

    Conclusions:

    • Pregnancy may lead to altered Zn metabolism, particularly reflected in pubic hair.
    • Scalp hair may not be a reliable indicator of Zn, Cu, and Mn status changes during pregnancy.
    • Further research is warranted to elucidate the mechanisms behind these observed trace element fluctuations in pubic hair.