[Rheohepatography in acute intestinal obstruction]

Area of Science:

• Hepatology
• Gastroenterology
• Surgical Pathology

Context:

• Strangulating intestinal obstruction presents a critical surgical emergency.
• Hepatic blood flow is vital for liver function and patient outcomes.
• Previous research has indicated potential hepatic complications in intestinal obstruction.

Purpose:

• To investigate the impact of strangulating intestinal obstruction on hepatic blood circulation.
• To evaluate the extent of hepatic blood flow reduction in affected patients and animal models.
• To identify therapeutic strategies for mitigating hepatic compromise in acute intestinal obstruction.

Summary:

• Rheohepatographic studies on 48 surgically treated patients and 62 dogs revealed significant disturbances in hepatic blood circulation.
• A notable reduction in hepatic volume blood flow was consistently observed.
• These findings underscore the detrimental effects of intestinal obstruction on liver perfusion.

Impact:

• Highlights the critical need for interventions aimed at normalizing hepatic and porto-hepatic circulation.
• Recommends therapeutic measures that protect the liver from detrimental factors during acute intestinal obstruction.
• Informs clinical practice regarding the management of hepatic complications in intestinal obstruction.