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Related Experiment Videos

Sensitivity and fragility in keratoconus.

M Millodot, H Owens

    Acta Ophthalmologica
    |October 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    This study found reduced corneal sensitivity and increased fragility in keratoconus patients, especially those wearing contact lenses. Central corneal touch threshold correlated with keratoconus severity in non-contact lens wearers.

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    Area of Science:

    • Ophthalmology
    • Corneal Diseases
    • Optometry

    Background:

    • Keratoconus is a progressive thinning of the cornea.
    • Corneal sensitivity and biomechanical properties are crucial for ocular health.

    Purpose of the Study:

    • To investigate corneal sensitivity and fragility in keratoconus patients.
    • To correlate these findings with keratoconus severity and contact lens wear.

    Main Methods:

    • Photokeratoscopy was used to assess keratoconus severity.
    • Corneal sensitivity was measured using the corneal touch threshold (CTT) in central and peripheral cornea.
    • Corneal fragility was assessed and compared between keratoconus and normal eyes.

    Main Results:

    Related Experiment Videos

  • Keratoconus patients exhibited significantly lower corneal sensitivity compared to normal eyes.
  • Eyes wearing contact lenses showed the lowest sensitivity.
  • A significant correlation was found between central CTT and keratoconus severity in eyes not wearing contact lenses.
  • Corneal fragility was elevated in keratoconus and further increased with contact lens wear, correlating significantly with severity.

    • Conclusions:

    • Keratoconus significantly impairs corneal sensitivity and increases fragility.
    • Contact lens wear exacerbates these effects.
    • Central corneal sensitivity is a potential indicator of keratoconus severity in specific patient groups.