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Endocarditis caused by Cardiobacterium hominis. Two case reports.

B Bruun, J Buch, E Kirkegaard

    Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. Section B, Microbiology
    |October 1, 1983
    PubMed
    Summary

    This study reports two cases of endocarditis caused by Cardiobacterium hominis, noting extensive valvular damage. Differentiating C. hominis involves specific biochemical tests like oxidase and indole production.

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    Area of Science:

    • Infectious Diseases
    • Microbiology
    • Cardiology

    Background:

    • Endocarditis is a serious infection affecting heart valves.
    • Gram-negative rods are a diverse group of bacteria, some of which can cause endocarditis.
    • Cardiobacterium hominis is a fastidious gram-negative bacterium that can be a rare cause of endocarditis.

    Observation:

    • Two cases of endocarditis caused by Cardiobacterium hominis were identified.
    • Patients presented with significant valvular damage upon hospitalization.
    • Clinical presentation did not reveal unusual features beyond the severity of valvular damage.

    Findings:

    • Cardiobacterium hominis was confirmed as the causative agent in both endocarditis cases.
    • Specific biochemical properties, including oxidase and catalase reactions, indole production, and carbohydrate fermentation patterns, distinguish C. hominis from other fastidious gram-negative rods.

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  • Extensive valvular damage was a notable characteristic in these patients.

    • Implications:

    • Early identification and differentiation of Cardiobacterium hominis are crucial for effective endocarditis treatment.
    • Understanding the specific biochemical profile of C. hominis aids in its laboratory identification.
    • The findings highlight the potential for severe valvular damage in C. hominis endocarditis, emphasizing the need for prompt diagnosis and intervention.