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Left ventricular function after long-term treatment with ventricular inhibited compared to atrial triggered
Summary
Atrial triggered ventricular (VAT) pacing offers significant hemodynamic advantages over ventricular inhibited (VVI) pacing, improving cardiac output and exercise capacity in patients with high-degree AV block.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Devices
Background:
- Long-term effects of different pacemaker modes on cardiac performance are crucial for patient management.
- Ventricular inhibited (VVI) and atrial triggered ventricular (VAT) pacing are common modes for managing high-degree AV block.
Purpose of the Study:
- To compare the long-term effects of VVI and VAT pacing on cardiac performance.
- To evaluate hemodynamic differences between VVI and VAT pacing at rest and during exercise.
Main Methods:
- Cardiac catheterization was performed at rest and during exercise in 9 patients with high-degree AV block.
- Hemodynamic parameters including cardiac output, stroke volume, and pressures were measured during VVI and VAT pacing.
Main Results:
- VAT pacing significantly increased resting cardiac output (22%) and stroke volume compared to VVI pacing.
- Mean working capacity increased by 12% with VAT pacing.
- During exercise, cardiac output increased by 40% with VAT pacing due to increased heart rate.
- Stroke work and atrial rate decreased with VAT pacing, suggesting potentially lower sympathetic activity.
Conclusions:
- Hemodynamic advantages of VAT pacing are sustained even after years of VVI pacing.
- VAT pacing demonstrates superior cardiac performance compared to VVI pacing in patients with high-degree AV block.
- The findings support the continued use of VAT pacing for optimizing cardiac function.