Circulating immune complexes in pollinosis and chronic bronchopathies. Effect of immunotherapy

The aim of this study is to investigate a possible presence of CIC in pollinic patients with or without specific immunotherapy and in bronchial asthmatic patients with or without immunotherapy. The determination of CIC is carried out by means of precipitation with 3.5% PEG and a posterior determination of C4 of the precipitates as well as optical density. In our results we have found either normal values or similar ones to the control group in all the groups of patients studied, and which therefore proves to us on the one hand that in pollinosis there are no elevated levels of CIC and on the other hand that immunotherapy does not modify the levels of CIC.