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Related Experiment Videos

Transient myopia following isosorbide dinitrate.

M E Dangel, P A Weber, C B Leier

    Annals of Ophthalmology
    |December 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Transient myopia occurred in a patient after taking isosorbide dinitrate. This vision change, linked to ciliary spasm, resolved with cycloplegia, marking the first reported case.

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    Area of Science:

    • Ophthalmology
    • Pharmacology

    Background:

    • Isosorbide dinitrate is a medication commonly used for angina.
    • Transient visual disturbances are rare side effects of nitrate medications.

    Observation:

    • A 38-year-old woman experienced temporary myopia after isosorbide dinitrate use.
    • This myopia was accompanied by reduced accommodation amplitude and AC/A ratio.

    Findings:

    • The transient myopia resolved with cycloplegia, suggesting a ciliary spasm mechanism.
    • This is the first documented instance of myopia induced by isosorbide dinitrate.

    Implications:

    • Ciliary spasm should be considered in patients presenting with acute myopia after nitrate administration.
    • Further research may explore the precise mechanism of nitrate-induced ciliary spasm.