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Choroidal melanomas and paving stone degeneration
Annals of Ophthalmology
|August 1, 1983
Summary
Choroidal melanomas can cause paving stone degeneration anterior to the tumor due to vascular compromise. This finding was also observed with choroidal nevi and metastatic carcinomas.
Area of Science:
- Ophthalmology
- Oncology
Background:
- Malignant melanoma of the choroid is a primary intraocular tumor.
- Peripheral retinal and choroidal changes can occur secondary to intraocular pathologies.
Observation:
- Five cases demonstrated paving stone degeneration anterior to choroidal melanoma.
- This degenerative pattern was also noted with a choroidal nevus and metastatic carcinoma.
Findings:
- Paving stone lesions are likely caused by choroidal insufficiency.
- Tumor-induced vascular compromise is the presumed mechanism for this insufficiency.
Implications:
- This association highlights a potential diagnostic sign for choroidal tumors.
- Understanding tumor-induced vascular changes is crucial in ophthalmology.