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Fungal-contaminated soft contact lenses
Abstract:
Examination of clinically seen fungal-contaminated soft contact lenses reveals fungus within the matrix of the lenses in a highly reproductive state. To study the potential hazard of fungal-contaminated soft contact lenses to the cornea, such lenses were placed on abraded corneas of ten rabbits. Sterile lenses were placed on the opposite abraded cornea of each rabbit as a control. Although no fungal keratitis was documented in this experiment, the persistent corneal epithelial disruption seen in seven rabbits, plus the highly reproductive state of the fungus within the lens suggests fungal-contaminated lenses may pose a significant risk to the patient. We recommend prompt replacement of contaminated lenses and instruction of the patient on proper lens hygiene.
Insights
Fungal contamination in soft contact lenses poses a significant risk to the cornea, even without causing fungal keratitis. Prompt replacement and proper lens hygiene are crucial for patient safety.
Area of Science:
- Ophthalmology
- Mycology
- Biomaterials Science
Background:
- Soft contact lenses can become contaminated with fungi, with the microorganisms found in a highly reproductive state within the lens matrix.
- Fungal contamination of contact lenses presents a potential hazard to the cornea, necessitating investigation into the associated risks.
Purpose of the Study:
- To evaluate the potential hazard of fungal-contaminated soft contact lenses to the cornea.
- To assess the clinical implications of fungal presence within soft contact lens materials.
Main Methods:
- Fungal-contaminated soft contact lenses were placed on abraded corneas of ten rabbits.
- Sterile lenses were used as a control on the opposite cornea of each rabbit.
- Corneal health and signs of infection were monitored post-application.
Main Results:
- No cases of fungal keratitis were documented in the experimental group.
- Persistent corneal epithelial disruption was observed in seven out of ten rabbits exposed to contaminated lenses.
- Fungi within the lens matrix were observed in a highly reproductive state.
Conclusions:
- Fungal-contaminated soft contact lenses may pose a significant risk to patients, evidenced by corneal epithelial disruption.
- The highly reproductive state of fungi within lenses underscores the potential for adverse ocular events.
- Prompt replacement of contaminated lenses and enhanced patient education on proper lens hygiene are recommended.