Massive ectopic calcification of the leg following nerve injury

Four cases showing massive ectopic calcifications in muscles of the lower leg combined with nerve paralysis following war injuries or traffic accident are reported. The development and increase of localized soft tissue calcifications were observed for several years. One case was treated by extirpating the ectopic calcified mass. Several operations were performed because of abnormalities in the feet as a sequel of nerve injury. No clear connection was observed between primary infection or reduced blood supply and development of calcification, although microtrauma of paretic muscle fibers is believed to cause partially induction of massive ectopic calcifications in the cases described.