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Cutaneous effects from occupational exposure to fenvalerate.

S B Tucker, S A Flannigan

    Archives of Toxicology
    |November 1, 1983
    PubMed
    Summary

    Agricultural workers reported paresthesia, a stinging or burning sensation progressing to numbness, after exposure to the synthetic pyrethroid fenvalerate. Environmental factors influenced the intensity of this cutaneous reaction.

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    Area of Science:

    • Agricultural Science
    • Toxicology
    • Dermatology

    Background:

    • Synthetic pyrethroids are widely used insecticides.
    • Fenvalerate exposure can lead to various health effects.
    • Cutaneous reactions to pesticides require thorough investigation.

    Purpose of the Study:

    • To determine the prevalence of skin reactions to fenvalerate.
    • To characterize the nature of these cutaneous responses.
    • To identify the circumstances and settings of fenvalerate exposure.

    Main Methods:

    • Field survey and case studies of agricultural workers.
    • Interviews and examinations of individuals with extensive fenvalerate exposure.
    • Documentation of reported sensations and observed clinical signs.

    Main Results:

    • All interviewed workers reported paresthesia associated with fenvalerate exposure.
    • The sensation was described as stinging/burning, progressing to numbness in about one-third of cases.
    • Reactions typically began hours after exposure, peaked in the evening, and were transient; no significant inflammation was observed.

    Conclusions:

    • Fenvalerate exposure in agricultural settings can cause transient paresthesia.
    • The intensity of the cutaneous sensation is influenced by exposure type, extent, and environmental factors.
    • Further research is needed to understand the mechanisms and long-term implications of fenvalerate-induced paresthesia.

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