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[Eosinophilic meningomyelitis. Report of a case]
Arquivos De Neuro-Psiquiatria
|December 1, 1983
Abstract:
A 31 years old man who developed paraplegia due to a meningomyelitis is reported. Cerebrospinal fluid examination showed 116 white cells with 57% eosinophils. On the 79th day the patient died from pulmonary embolism. On post mortem examination no eosinophilic infiltrations was found. However, a detailed histologic examination was not performed.
Insights
A patient developed paraplegia from meningomyelitis with high eosinophils in cerebrospinal fluid. Despite initial findings, post-mortem examination revealed no eosinophilic infiltrations, highlighting diagnostic challenges.
Area of Science:
- Neurology
- Immunology
- Pathology
Background:
- Meningomyelitis can cause severe neurological deficits, including paraplegia.
- Eosinophilic meningitis is a rare condition characterized by the presence of eosinophils in the cerebrospinal fluid.
- The differential diagnosis for eosinophilic meningitis is broad and includes infectious, inflammatory, and neoplastic causes.
Observation:
- A 31-year-old male presented with paraplegia secondary to meningomyelitis.
- Cerebrospinal fluid analysis revealed elevated white blood cell count (116 cells) with a significant proportion of eosinophils (57%).
- The patient succumbed to pulmonary embolism on the 79th day of illness.
Findings:
- Post-mortem examination did not reveal any eosinophilic infiltrations in the affected tissues.
- The absence of histological evidence of eosinophilic infiltration at autopsy contrasts with the cerebrospinal fluid findings.
- A comprehensive histological examination was not performed, limiting definitive conclusions.
Implications:
- This case underscores the potential discrepancy between cerebrospinal fluid findings and post-mortem histological examination in diagnosing eosinophilic meningitis.
- It highlights the diagnostic challenges associated with eosinophilic meningitis and the need for thorough investigation.
- Further research into the pathogenesis and diagnostic markers of eosinophilic meningitis is warranted.