Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Muscle Contraction01:15

Muscle Contraction

Muscle Contraction01:10

Muscle Contraction

In skeletal muscles, acetylcholine is released by nerve terminals at the motor endplate—the point of synaptic communication between motor neurons and muscle fibers. The binding of acetylcholine to its receptors on the sarcolemma allows entry of sodium ions into the cell and triggers an action potential in the muscle cell. Thus, electrical signals from the brain are transmitted to the muscle. Subsequently, the enzyme acetylcholinesterase breaks down acetylcholine to prevent excessive muscle...
Anatomical Movements00:51

Anatomical Movements

Anatomical movements refer to the various actions or motions that can be performed by the body's joints and muscles. These movements are described using specific terms to provide a standardized way of discussing and understanding the range of motion at different joints.
Here are some common anatomical movements:
Flexion and extension motions are in the sagittal (anterior–posterior) plane of motion. These movements take place at the shoulder, hip, elbow, knee, wrist, metacarpophalangeal,...
Motor Units01:13

Motor Units

The motor unit is a fundamental component of the neuromuscular system and plays a crucial role in coordinating muscle contractions. It consists of a somatic motor neuron, which connects and controls multiple skeletal muscle fibers, forming a single functional segment. The axon of the motor neuron branches out and establishes synaptic connections known as neuromuscular junctions with individual muscle fibers within the motor unit.
Motor units come in different sizes, with smaller units...
Motor Unit Stimulation01:20

Motor Unit Stimulation

When the neuron of a motor unit fires an action potential, it triggers a series of events, leading to a twitch contraction in the muscle fibers. The process of excitation-contraction coupling is crucial in relaying the action potential to the muscle fibers.
The latent period of contraction marks the onset of excitation-contraction coupling, when the action potential propagates across the sarcolemma, preparing the muscle fibers for contraction. As the fibers enter the contraction phase, the...
Direct Motor Pathways01:11

Direct Motor Pathways

The direct motor pathways, also known as the pyramidal tracts, are a group of neural pathways that originate in the brain and descend through the spinal cord. They control the voluntary movement of the body. There are two major direct motor pathways: the corticospinal and the corticobulbar tracts.
The corticospinal tract is responsible for the voluntary movement of the limbs and trunk. It originates in the cerebral cortex of the brain and descends through the cerebrum's internal capsule and the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Italian Right Hemisphere Language Battery: the normative study.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·2005
Same author

Rivastigmine superior to aspirin plus nimodipine in subcortical vascular dementia: an open, 16-month, comparative study.

International journal of clinical practice·2004
Same author

Corticobasal degeneration: structural and functional MRI and single-photon emission computed tomography.

Neuroradiology·2003
Same author

'Speech initiation hesitation' following subthalamic nucleus stimulation in a patient with Parkinson's disease.

European neurology·2003
Same author

Learned movements in a left-handed pianist: an f-MRI evaluation.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2003
Same author

Crying of a newborn child: alarm signal or protocommunication?

Perceptual and motor skills·2003

Related Experiment Video

Updated: Jul 18, 2026

Functional Isolation of Single Motor Units of Rat Medial Gastrocnemius Muscle
06:54

Functional Isolation of Single Motor Units of Rat Medial Gastrocnemius Muscle

Published on: December 26, 2020

Fastigial unit activity during voluntary movement in primates.

A Bava, R J Grimm, D S Rushmer

    Brain Research
    |December 12, 1983
    PubMed
    Summary

    The cerebellum's fastigial nucleus offers rapid feedback for spinal movement information to higher brain areas. This pathway processes crucial force-velocity data, aiding motor control corrections.

    Area of Science:

    • Neuroscience
    • Motor Control
    • Cerebellar Function

    Background:

    • The cerebellum plays a critical role in motor coordination and learning.
    • Understanding feedback pathways is essential for deciphering motor control mechanisms.

    Purpose of the Study:

    • To investigate if the fastigial nucleus of the cerebellum acts as a rapid feedback pathway.
    • To determine if this pathway transmits spinal movement information to suprasegmental structures.

    Main Methods:

    • Macaca irus monkeys were trained in voluntary wrist movements (flexion/extension).
    • Fastigial neuron activity was recorded and correlated with movement parameters (force, velocity, position) and muscle activity.

    Main Results:

    • Fastigial neurons were uniformly recruited post-movement onset, processing force-velocity information.

    More Related Videos

    In Vivo Wireless Optogenetic Control of Skilled Motor Behavior
    07:52

    In Vivo Wireless Optogenetic Control of Skilled Motor Behavior

    Published on: November 22, 2021

    "Avatar", a Modified Ex vivo Work Loop Experiments Using In vivo Strain and Activation
    07:03

    "Avatar", a Modified Ex vivo Work Loop Experiments Using In vivo Strain and Activation

    Published on: August 18, 2023

    Related Experiment Videos

    Last Updated: Jul 18, 2026

    Functional Isolation of Single Motor Units of Rat Medial Gastrocnemius Muscle
    06:54

    Functional Isolation of Single Motor Units of Rat Medial Gastrocnemius Muscle

    Published on: December 26, 2020

    In Vivo Wireless Optogenetic Control of Skilled Motor Behavior
    07:52

    In Vivo Wireless Optogenetic Control of Skilled Motor Behavior

    Published on: November 22, 2021

    "Avatar", a Modified Ex vivo Work Loop Experiments Using In vivo Strain and Activation
    07:03

    "Avatar", a Modified Ex vivo Work Loop Experiments Using In vivo Strain and Activation

    Published on: August 18, 2023

  • Specific units correlated with force or velocity independently.
  • 75% of recorded units participated in processing movement data.
  • Conclusions:

    • The fastigial nucleus provides a fast feedback pathway for spinal movement information.
    • This pathway is strategically positioned to send corrective signals for motor performance.